Set in a future post-scarcity dystopian world in which everyone is turned "Pretty" by extreme cosmetic surgery upon reaching age 16, Uglies tells the story of teenager Tally Youngblood who rebels against society's enforced conformity.
In the story, the people who first founded New Pretty Town and Uglyville created the operation to help prevent war and anger...which had caused the extinction of the "Rusties". Living in a world of diminished resources and high technology, a reduced population has retreated into a relatively few metropolises after an unremembered global catastrophe, leaving behind the "Rusty Ruins" of decaying cities in the abandoned stretches of countryside. Society is structured into a rigid caste system of littlies (children), uglies (adolescents), new pretties (teenagers and young adults), middle and late pretties (adults), and crumblies (retired adults). The city-state governments administer the cosmetic surgery to foster conformity, purging humanity of ruinous competition and jealousy.

Uglies "plays on adolescent changes, both physical and emotional." The book and series as whole addresses the issues of conformity, body image and individuality, as well as the impact of strong peer pressure.

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